VERSION HISTORY

Old vs New Schedule M

Explore the exact textual changes between the old Schedule M and the Revised Schedule M (2025). Our comparison tool highlights added and removed requirements, making gap analysis easier for your facility.

5 clauses modified10 new clauses added0 clauses removed
Clause 7.3Quality Control
new

New OOS handling requirement with 30-day investigation deadline

Old Schedule M

No corresponding clause existed.

Revised Schedule M

Written procedures shall be established for handling Out-of-Specification results. All OOS investigations shall be completed within 30 days. The batch shall not be released until the OOS investigation is satisfactorily completed.